Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17864622 | 0.80 | ACHE (0.46) | ALDH1A1HPGDHSD17B10HTR2AHTR2C | |
| SCHEMBL18007684 | 0.79 | HTR2A (0.40) | ALDH1A1HTR2AHTR2CMAP3K14ERN1 | |
| SCHEMBL13256218 | 0.79 | ERN1 (0.45) | MAP3K14ERN1GAAMAPTTRPV4 | |
| SCHEMBL19871663 | 0.77 | HTR2A (0.38) | ALDH1A1HTR2AHTR2CERN1AR | |
| SCHEMBL19871672 | 0.77 | HTR2A (0.38) | ALDH1A1HTR2AHTR2CMAP3K14ERN1 | |
| SCHEMBL13696501 | 0.75 | HSD11B1 (0.37) | ALDH1A1HSD17B10MAPTTMPRSS4 | |
| SCHEMBL13550053 | 0.75 | TMPRSS4 (0.36) | ARMAPTTMPRSS4 | |
| SCHEMBL25958932 | 0.74 | ERN1 (0.39) | HPGDMAP3K14ERN1LMNAGAA | |
| SCHEMBL11425977 | 0.73 | MAP3K14 (0.46) | MAP3K14ERN1GAAMAPTTRPV4 | |
| SCHEMBL10118361 | 0.73 | MAPT (0.42) | ALDH1A1HPGDHSD17B10HTR2CMAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888749-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2021-10-06 | — | — | EP | disclosed |
| EP-3578547-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2019-12-11 | — | — | EP | disclosed |