Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141700 | 0.77 | KDM4E (0.36) | NOTUMGAANPSR1L3MBTL1HSD17B10 | |
| SCHEMBL30211465 | 0.75 | L3MBTL1 (0.34) | NOTUMGAANPSR1L3MBTL1PTGS2 | |
| SCHEMBL20562638 | 0.72 | NR4A2 (0.42) | NOTUMHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL1966318 | 0.72 | NPSR1 (0.37) | NOTUMGAANPSR1L3MBTL1HSD17B10 | |
| SCHEMBL4131647 | 0.71 | NR1H2 (0.42) | NOTUML3MBTL1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29155899 | 0.70 | NPSR1 (0.36) | NOTUMGAANPSR1L3MBTL1HSD17B10 | |
| SCHEMBL22759625 | 0.70 | SMN1; SMN2 (0.35) | NOTUMGAAHSD17B10PTGS2KDM4E | |
| SCHEMBL20562649 | 0.70 | KDM4E (0.38) | NOTUMNPSR1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1254373 | 0.70 | CYP1A2 (0.46) | NOTUMNPSR1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL15230862 | 0.67 | SMN1; SMN2 (0.37) | NOTUMGAANPSR1L3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019233457-A1 | ERK INHIBITOR AND USE THEREOF | 贝达药业股份有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |