Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21588737 | 0.86 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL13956744 | 0.82 | ALDH1A1 (0.72) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14096078 | 0.81 | MAPT (0.81) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL12316694 | 0.81 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14096079 | 0.81 | MAPT (0.78) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2345780 | 0.80 | EPHX1 (0.68) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13166709 | 0.80 | MAPT (0.77) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28662121 | 0.80 | SIRT1 (0.68) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14096080 | 0.80 | MAPT (0.76) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9133486 | 0.79 | NPC1 (0.65) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019233474-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2019-12-12 | — | — | WO | disclosed |