Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.90 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.90 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.82 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.82 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sch-58261 SCHEMBL537287 | 0.90 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL21588752 | 0.90 | ADORA2A (0.78) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL7339226 | 0.90 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL23691785 | 0.90 | ADORA2A (0.85) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL23691615 | 0.89 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL21588926 | 0.88 | ADORA2A (0.91) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL21588760 | 0.88 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL22796280 | 0.88 | ADORA2A (0.85) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL20694157 | 0.88 | ADORA2A (0.85) | ADORA2AADORA1ADORA2BKDM4ENPC1 | |
| SCHEMBL7346016 | 0.85 | ADORA2A (0.90) | ADORA2AADORA1ADORA2BKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230171-A1 | SELECTIVE A2A RECEPTOR ANTAGONIST | INXMED (NANJING) CO., LTD. (CN) | 2021-07-29 | — | — | US | disclosed |
| EP-3805225-A1 | SELECTIVE A2a RECEPTOR ANTAGONIST | Inxmed (Nanjing) Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019233366-A1 | SELECTIVE A2A RECEPTOR ANTAGONIST | 应世汇康（北京）生物科技有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230171-A1 | SELECTIVE A2A RECEPTOR ANTAGONIST | ADORA2A, ADORA2B, ADORA1 | ADORA2A 1/4885ADORA1 3/4885ADORA2B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.