Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462824 | 1.00 | NR1H4 (0.34) | NR1H4SLC10A2 | |
| SCHEMBL29462856 | 0.97 | NR1H4 (0.35) | NR1H4SLC10A2 | |
| SCHEMBL21589524 | 0.97 | NR1H4 (0.35) | NR1H4SLC10A2 | |
| SCHEMBL21589511 | 0.93 | NR1H4 (0.40) | NR1H4SLC10A2 | |
| SCHEMBL29462832 | 0.93 | NR1H4 (0.40) | NR1H4SLC10A2 | |
| SCHEMBL29462877 | 0.93 | NR1H4 (0.40) | NR1H4SLC10A2 | |
| SCHEMBL21589512 | 0.93 | NR1H4 (0.40) | NR1H4SLC10A2 | |
| SCHEMBL29189023 | 0.93 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL22476267 | 0.92 | NR1H4 (0.36) | NR1H4SLC10A2 | |
| SCHEMBL28527722 | 0.92 | NR1H4 (0.36) | NR1H4SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-B1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2023-01-18 | — | — | EP | disclosed |
| US-20210017141-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2021-01-21 | — | — | US | disclosed |
| US-10793534-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2020-10-06 | — | — | US | disclosed |
| WO-2019234077-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793534-B2 | Benzothia(di)azepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | NR1H4 7/4885SLC10A2 2/4885 |
| US-20210017141-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | NR1H4 7/4885SLC10A2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.