Cearoin

Cearoin

SCHEMBL2158951

COc1c(O)cc(C(=O)c2ccccc2)c(O)c1C.COc1cc(O)c(C(=O)c2ccccc2)cc1O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.75
LMNA P02545 5/20 0.75
HPGD P15428 3/20 0.75
KDM4E B2RXH2 2/20 0.75
HSD17B10 Q99714 2/20 0.75
CYP3A4 P08684 1/20 0.75
RECQL P46063 1/20 0.75
KMT2A Q03164 3/20 0.55
ALDH1A1 P00352 2/20 0.55
MAPK1 P28482 2/20 0.50
ALOX15 P16050 1/20 0.50
HTT P42858 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C19 P33261 2/20 0.49
PGR P06401 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
HRH1 P35367 1/20 0.49
SLC6A3 Q01959 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cearoin SCHEMBL4928735 0.87 MAPT (1.00) MAPTLMNAHPGDKDM4EHSD17B10
Cearoin SCHEMBL29874650 0.87 MAPT (1.00) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL27946121 0.81 MAPT (0.88) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL2474578 0.80 MAPT (0.60) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL27864162 0.80 LMNA (0.60) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL9339940 0.79 MAPT (0.84) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL5069910 0.79 HPGD (0.52) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL27567451 0.79 MAPT (0.57) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL7606487 0.78 LMNA (0.77) MAPTLMNAHPGDKDM4EHSD17B10
SCHEMBL29665888 0.78 LMNA (0.77) MAPTLMNAHPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985702-B2 Woven fabric for airbag TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-07-26 US disclosed
US-20100260976-A1 WOVEN FABRIC FOR AIRBAG TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-10-14 US disclosed
EP-1371682-B1 Polyester film for display MITSUBISHI POLYESTER FILM CORP (JP) 2008-05-21 EP disclosed
US-6921580-B2 Polyester film for display MITSUBISHI POLYESTER FILM CORPORATION (JP) 2005-07-26 US disclosed
US-20030235704-A1 Polyester film for display MITSUBISHI CHEMICAL CORPORATION (JP) 2003-12-25 US disclosed
EP-1371682-A2 Polyester film for display Mitsubishi Polyester Film Corporation (JP) 2003-12-17 EP disclosed