Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589579 | 0.97 | LMNA (0.30) | LMNAHTT | |
| SCHEMBL21589480 | 0.89 | NR1H4 (0.33) | ACAT1 | |
| SCHEMBL21589585 | 0.89 | RARB (0.32) | — | |
| SCHEMBL21589672 | 0.86 | PDK1 (0.30) | — | |
| SCHEMBL21589484 | 0.85 | RARB (0.31) | — | |
| SCHEMBL21589780 | 0.85 | — | — | |
| SCHEMBL24940297 | 0.84 | — | — | |
| SCHEMBL21589587 | 0.83 | NR1H4 (0.34) | CNR1CNR2ACAT1 | |
| SCHEMBL22476233 | 0.83 | NR1H4 (0.33) | CNR1CNR2 | |
| SCHEMBL21589631 | 0.83 | GRM2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802504-B1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2023-01-18 | — | — | EP | disclosed |
| WO-2019234077-A1 | BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2019-12-12 | — | — | WO | disclosed |