Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 20/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983451 | 0.84 | HPGD (0.67) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL24107693 | 0.80 | HPGD (0.54) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21589936 | 0.76 | MAPT (0.60) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL23515735 | 0.74 | MAPT (0.58) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21319129 | 0.74 | HPGD (0.54) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15525575 | 0.72 | HPGD (1.00) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22939512 | 0.71 | HPGD (0.69) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL18962635 | 0.70 | HPGD (0.67) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL19416825 | 0.70 | HPGD (0.72) | HPGDKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15583810 | 0.70 | HPGD (0.71) | HPGDKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019234197-A1 | THIENO[2,3-B]PYRIDINE DERIVATIVES AS EPAC INHIBITORS AND THEIR PHARMACEUTICAL USES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2019-12-12 | — | — | WO | disclosed |