Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | UTRN | P46939 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26981436 | 0.91 | UTRN (0.34) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30711175 | 0.91 | UTRN (0.34) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL26981416 | 0.87 | ALDH1A1 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29900337 | 0.87 | ALDH1A1 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL25418156 | 0.85 | UTRN (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30970967 | 0.82 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL19302014 | 0.82 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL21589996 | 0.81 | HDAC3 (0.31) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20734008 | 0.80 | UTRN (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL21586220 | 0.79 | HDAC3 (0.31) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4342297-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| WO-2019234158-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | AADAC, ACHE, DDT | HDAC3 349/4885HDAC1 118/4885HDAC2 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.