⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29207844 | 0.83 | ALDH1A1 (0.38) | — | |
| SCHEMBL27822840 | 0.76 | — | — | |
| SCHEMBL16958344 | 0.76 | — | — | |
| SCHEMBL220659 | 0.76 | NQO1 (0.36) | — | |
| SCHEMBL21268243 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL160506 | 0.73 | — | — | |
| SCHEMBL105204 | 0.73 | CA1 (0.48) | — | |
| SCHEMBL17046353 | 0.73 | HPGD (0.38) | — | |
| SCHEMBL161096 | 0.71 | — | — | |
| SCHEMBL194173 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1690 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| CN-117700417-A | Deoxidized duckbill ketone base derivative and preparation method and application thereof | 安徽医科大学 | 2024-03-15 | — | — | CN | claimed |
| CN-113773242-B | Indol-2-one BRD4 inhibitor and preparation and application thereof | 兰州大学 | 2023-10-27 | — | — | CN | claimed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | claimed |
| CN-115232070-B | Quinolinone alkaloid derivative containing acylhydrazone group on 1-position nitrogen atom, and preparation method and application thereof | 太原理工大学 | 2023-06-30 | — | — | CN | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| CN-115368218-A | Method for preparing 4-diaryl methyl substituted phenol compound | 湖南理工学院 | 2022-11-22 | — | — | CN | claimed |
| US-20220168322-A1 | NOVEL STAT3 INHIBITORS IDENTIFIED BY STRUCTURE-BASED VIRTUAL SCREENING INCORPORATING SH2 DOMAIN FLEXIBILITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2022-06-02 | — | — | US | claimed |
| CN-110003176-B | Amide-containing benzimidazole compound and application thereof | 沈阳药科大学 | 2021-12-21 | — | — | CN | claimed |
| EP-0706514-B1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1998-11-18 | — | — | EP | claimed |
| JP-H09502702-A | — | — | 1997-03-18 | — | — | JP | claimed |
| EP-0706514-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1996-04-17 | — | — | EP | claimed |
| US-5409934-A | Antiallergens | BEECHAM GROUP P.L.C. (GB) | 1995-04-25 | — | — | US | claimed |
| WO-1995006034-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1995-03-02 | — | — | WO | claimed |
| EP-0563168-A1 | XANTHINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1993-10-06 | — | — | EP | claimed |
| US-5231105-A | Ethylamine derivatives and antihypertensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-07-27 | — | — | US | claimed |
| WO-1992011260-A1 | XANTHINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-07-09 | — | — | WO | claimed |
| US-4440845-A | CHARGE TRANSFER COMPOUND | RICOH CO., LTD. (JP) | 1984-04-03 | — | — | US | claimed |
| US-3932503-A | Benzenesulfonyl ureas | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | claimed |