Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21586207 | 0.85 | POLB (0.41) | CYP1A2POLBOPRM1ALDH1A1TRPM8 | |
| SCHEMBL20276049 | 0.85 | POLB (0.39) | CYP1A2POLBALDH1A1TRPM8 | |
| SCHEMBL31476225 | 0.84 | POLB (0.36) | CYP1A2POLBALDH1A1TRPM8 | |
| SCHEMBL31476271 | 0.84 | POLB (0.36) | CYP1A2POLBALDH1A1TRPM8 | |
| SCHEMBL24696315 | 0.83 | POLB (0.38) | CYP1A2POLBALDH1A1TRPM8 | |
| SCHEMBL21586224 | 0.83 | POLB (0.38) | CYP1A2POLBALDH1A1TRPM8TNF | |
| SCHEMBL30122103 | 0.83 | POLB (0.38) | CYP1A2POLBALDH1A1TRPM8TNF | |
| SCHEMBL30122116 | 0.83 | POLB (0.38) | CYP1A2POLBALDH1A1TRPM8TNF | |
| SCHEMBL21589986 | 0.79 | CYP1A2 (0.36) | CYP1A2POLBALDH1A1 | |
| SCHEMBL24576633 | 0.77 | POLB (0.39) | CYP1A2POLBTRPM8LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019234158-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-12 | — | — | WO | disclosed |