Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21589986 | 0.94 | CYP1A2 (0.36) | POLBCYP1A2ALDH1A1 | |
| SCHEMBL21590016 | 0.91 | POLB (0.41) | POLB | |
| SCHEMBL20267583 | 0.87 | POLB (0.42) | POLBCYP1A2PDE10A | |
| SCHEMBL30122217 | 0.87 | POLB (0.42) | POLBCYP1A2PDE10A | |
| SCHEMBL21590031 | 0.86 | POLB (0.45) | POLBALDH1A1 | |
| SCHEMBL21590008 | 0.86 | AGPAT2 (0.40) | CYP1A2PDE10AOPRM1 | |
| SCHEMBL21590034 | 0.85 | CYP1A2 (0.39) | POLBCYP1A2TRPM8ALDH1A1OPRM1 | |
| SCHEMBL22036956 | 0.83 | POLB (0.41) | POLBPDE10A | |
| SCHEMBL16002332 | 0.83 | POLB (0.45) | POLBCYP1A2ALDH1A1PDE10A | |
| SCHEMBL20628414 | 0.83 | POLB (0.40) | POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802542-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-28 | — | — | EP | disclosed |
| US-20250081967-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-13 | — | — | US | disclosed |
| CN-119431377-A | Pesticidally active heterocyclic derivatives with sulfoximine containing substituents | 先正达农作物保护股份公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-4347591-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| EP-4342297-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-18 | — | — | US | disclosed |
| WO-2022253841-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022253841-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-12-08 | — | — | WO | disclosed |
| EP-3802542-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2021-04-14 | — | — | EP | disclosed |
| WO-2019234158-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150944-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | AADAC, ACHE, DDT | POLB 4289/4885CYP1A2 337/4885TRPM8 3977/4885 |
| US-20250081967-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | DDT, AADAC, SMOX | POLB 4001/4885CYP1A2 348/4885TRPM8 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.