Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21590034 | 0.85 | CYP1A2 (0.39) | POLBTRPM8ALDH1A1CYP1A2 | |
| SCHEMBL20267583 | 0.85 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL30122217 | 0.85 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL17844096 | 0.84 | POLB (0.39) | POLBTRPM8ALDH1A1 | |
| SCHEMBL29904936 | 0.84 | POLB (0.39) | POLBTRPM8ALDH1A1 | |
| SCHEMBL31476231 | 0.84 | POLB (0.37) | POLBTRPM8 | |
| SCHEMBL22036969 | 0.84 | POLB (0.37) | POLBTRPM8 | |
| SCHEMBL31476252 | 0.84 | POLB (0.37) | POLBTRPM8 | |
| SCHEMBL20628414 | 0.83 | POLB (0.40) | POLBCYP1A2 | |
| SCHEMBL24695966 | 0.83 | POLB (0.38) | POLBTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018108726-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-21 | — | — | WO | disclosed |