Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21590303 | 0.86 | MEN1 (0.45) | KMT2AMEN1POLBKDM2BHSD11B1 | |
| SCHEMBL4040222 | 0.82 | MEN1 (0.47) | KMT2AMEN1POLBHSD11B1MGLL | |
| SCHEMBL232050 | 0.78 | NPC1 (0.47) | KMT2AMEN1POLBHSD11B1MGLL | |
| SCHEMBL4190126 | 0.78 | MGLL (0.51) | KMT2AALDH1A1GAAMEN1POLB | |
| SCHEMBL23722789 | 0.77 | CHRNB2 (0.45) | ALDH1A1GAA | |
| SCHEMBL5214996 | 0.75 | SRD5A2 (0.55) | KMT2AALDH1A1MEN1HSD11B1MGLL | |
| SCHEMBL27514751 | 0.75 | SRD5A2 (0.50) | KMT2AMEN1HSD11B1MGLL | |
| SCHEMBL5218499 | 0.73 | SRD5A2 (0.58) | KMT2AALDH1A1MEN1POLB | |
| SCHEMBL744542 | 0.70 | POLB (0.64) | KMT2AMEN1POLB | |
| SCHEMBL25292565 | 0.70 | POLB (0.43) | KMT2AALDH1A1MEN1POLBHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238067-A1 | PYRROLO [2, 3-B] PYRIDINES OR PYRROLO [2, 3-B] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2019-12-19 | — | — | WO | disclosed |