Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | LSS | P48449 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030502 | 0.89 | DRD2 (0.42) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL1033569 | 0.89 | DRD2 (0.42) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL1031360 | 0.89 | DRD2 (0.42) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL13006443 | 0.81 | DRD2 (0.65) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL2077235 | 0.81 | DRD2 (0.65) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL11893151 | 0.81 | DRD2 (0.65) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL23469162 | 0.80 | SLC6A2 (0.55) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL12950820 | 0.80 | SLC6A2 (0.55) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL24394469 | 0.79 | KCNH2 (0.54) | DRD2DRD3LSSKCNH2SLC6A2 | |
| SCHEMBL24310166 | 0.79 | SLC6A2 (0.54) | DRD2DRD3LSSKCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238067-A1 | PYRROLO [2, 3-B] PYRIDINES OR PYRROLO [2, 3-B] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2019-12-19 | — | — | WO | disclosed |