Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.76 |
| ▸ | DRD1 | P21728 | 9/20 | 0.76 |
| ▸ | DRD4 | P21917 | 9/20 | 0.76 |
| ▸ | DRD5 | P21918 | 9/20 | 0.76 |
| ▸ | DRD3 | P35462 | 9/20 | 0.76 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352405 | 0.86 | DRD2 (1.00) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL21590355 | 0.85 | DRD2 (0.64) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4096013 | 0.83 | DRD2 (0.64) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL9956909 | 0.82 | DRD2 (0.62) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL16520806 | 0.81 | DRD2 (0.63) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL22444937 | 0.80 | DRD2 (0.60) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL28513880 | 0.79 | DRD2 (0.53) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL2278508 | 0.79 | DRD2 (0.60) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL21590216 | 0.79 | DRD2 (0.74) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL12852526 | 0.77 | HTR2A (0.56) | DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238067-A1 | PYRROLO [2, 3-B] PYRIDINES OR PYRROLO [2, 3-B] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2019-12-19 | — | — | WO | disclosed |