Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.79 |
| ▸ | TOP1 | P11387 | 19/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591945 | 0.93 | TOP1 (0.79) | SLC2A1TOP1 | |
| SCHEMBL21450474 | 0.93 | SLC2A1 (0.89) | SLC2A1TOP1 | |
| SCHEMBL31312530 | 0.93 | SLC2A1 (0.89) | SLC2A1TOP1 | |
| SCHEMBL23255477 | 0.92 | TOP1 (0.76) | SLC2A1TOP1 | |
| SCHEMBL26852565 | 0.91 | SLC2A1 (0.74) | SLC2A1TOP1 | |
| SCHEMBL26294990 | 0.90 | SLC2A1 (0.72) | SLC2A1TOP1 | |
| SCHEMBL21564110 | 0.89 | TOP1 (0.87) | SLC2A1TOP1 | |
| SCHEMBL24642747 | 0.89 | TOP1 (0.86) | SLC2A1TOP1 | |
| SCHEMBL23255710 | 0.88 | TOP1 (0.72) | SLC2A1TOP1 | |
| SCHEMBL21592225 | 0.88 | TOP1 (0.72) | SLC2A1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590796-B | Camptothecin derivative and preparation method and application thereof | 青岛海洋生物医药研究院股份有限公司 | 2022-07-15 | — | — | CN | disclosed |
| US-20220177485-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
| US-20220177485-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
| EP-3808751-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Marine Biomedical Research Institute Of Qingdao Co., Ltd. (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-3808751-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Marine Biomedical Research Institute Of Qingdao Co., Ltd. (CN) | 2021-04-21 | — | — | EP | disclosed |
| US-20200231596-A1 | MATTER OF COMPOSITION, SYNTHESIS, FORMULATION AND APPLICATION OF FL118 PLATFORM POSITIONS 7 AND 9-DERIVED ANALOGUES FOR TREATMENT OF HUMAN DISEASE | CANGET BIOTEKPHARMA | 2020-07-23 | — | — | US | disclosed |
| CN-110590796-A | Camptothecin derivative and preparation method and application thereof | 青岛海洋生物医药研究院股份有限公司 | 2019-12-20 | — | — | CN | disclosed |
| WO-2019238046-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 青岛海洋生物医药研究院股份有限公司 | 2019-12-19 | — | — | WO | disclosed |
| WO-2019238046-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 青岛海洋生物医药研究院股份有限公司 | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231596-A1 | MATTER OF COMPOSITION, SYNTHESIS, FORMULATION AND APPLICATION OF FL118 PLATFORM POSITIONS 7 AND 9-DERIVED ANALOGUES FOR TREATMENT OF HUMAN DISEASE | TP53, BRCA1, MET | SLC2A1 4162/4885TOP1 2368/4885 |
| US-20220177485-A1 | CAMPTOTHECIN DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | WEE1, WASF2, WEE2 | SLC2A1 1886/4885TOP1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.