Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712227 | 0.97 | DNM1 (0.60) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Water SCHEMBL30848552 | 0.94 | DNM1 (0.57) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Bromide SCHEMBL21591925 | 0.90 | DNM1 (0.71) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL29712240 | 0.86 | DNM1 (0.70) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL30848505 | 0.86 | DNM1 (0.60) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Dodecylamine SCHEMBL7950250 | 0.85 | DNM1 (0.65) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| Bromide SCHEMBL126636 | 0.85 | DNM1 (0.81) | DNM1ALDH1A1TSHRTDP1CYP3A4 | |
| Bromide SCHEMBL7214979 | 0.85 | DNM1 (0.81) | DNM1ALDH1A1TSHRTDP1CYP3A4 | |
| Bromide SCHEMBL302420 | 0.85 | DNM1 (0.81) | DNM1ALDH1A1TSHRTDP1CYP3A4 | |
| Butylamine SCHEMBL23209722 | 0.82 | DNM1 (0.50) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101565659-B | Cleaning agent for fuel oil system of automotive engine | BEIJING HECHUANG TONGSHENG SCIENCE & TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | claimed |
| CN-101565659-A | Cleaning agent for fuel oil system of automotive engine | BEIJING HECHUANG TONGSHENG TEC (CN) | 2009-10-28 | — | — | CN | claimed |
| US-12024756-B2 | Countercurrent rare earth separation process | Seren Technologies Limited (GB) | 2024-07-02 | — | — | US | disclosed |
| US-11958754-B2 | Enhanced separation of rare earth metals | Seren Technologies Limited (GB) | 2024-04-16 | — | — | US | disclosed |
| WO-2024063017-A1 | CARBON DIOXIDE ABSORBENT AND METHOD FOR SEPARATING AND RECOVERING CARBON DIOXIDE | 日本化学工業株式会社 | 2024-03-28 | — | — | WO | disclosed |
| US-11401579-B2 | Rare earth metal oxide process including extracting rare earth metal from acidic solution with an ionic liquid composition | Seren Technologies Limited (GB) | 2022-08-02 | — | — | US | disclosed |
| US-20210285072-A1 | COUNTERCURRENT RARE EARTH SEPARATION PROCESS | Seren Technologies Limited (GB) | 2021-09-16 | — | — | US | disclosed |
| US-20210254191-A1 | RARE EARTH METAL OXIDE PREPARATION | Seren Technologies Limited (GB) | 2021-08-19 | — | — | US | disclosed |
| EP-3807431-A1 | RARE EARTH METAL OXIDE PREPARATION | Seren Technologies Limited (GB) | 2021-04-21 | — | — | EP | disclosed |
| EP-3807242-A1 | ENHANCED SEPARATION OF RARE EARTH METALS | Seren Technologies Limited (GB) | 2021-04-21 | — | — | EP | disclosed |
| EP-3807430-A1 | COUNTERCURRENT RARE EARTH SEPARATION PROCESS | Seren Technologies Limited (GB) | 2021-04-21 | — | — | EP | disclosed |
| CN-101565659-A | Cleaning agent for fuel oil system of automotive engine | BEIJING HECHUANG TONGSHENG TEC (CN) | 2009-10-28 | — | — | CN | disclosed |
| CN-1086914-C | Water insoluble polyquaternary phosphonium salt germicide | CHINA PETROCHEMICAL CORP (CN) | 2002-07-03 | — | — | CN | disclosed |
| CN-1086912-C | Water insoluble polyquaternary salt germicide | CHINA PETROCHEMICAL CORP (CN) | 2002-07-03 | — | — | CN | disclosed |
| CN-1086913-C | Water-insoluble disinfectant of poly quaternary salt type | CHINA PETROCHEMICAL CORP (CN) | 2002-07-03 | — | — | CN | disclosed |
| CN-1062714-C | Water insoluble polyquaternary phosphonium salt type germicide | CHINA PETROCHEMICAL CORP (CN) | 2001-03-07 | — | — | CN | disclosed |
| CN-1256078-A | Water insoluble polyquaternary phosphonium salt germicide | CHINA PETROCHEMICAL CORP (CN) | 2000-06-14 | — | — | CN | disclosed |
| CN-1252942-A | Water-insoluble disinfectant of poly quaternary salt type | CHINA PETROCHEMICAL CORP (CN) | 2000-05-17 | — | — | CN | disclosed |
| CN-1252222-A | Water insoluble polyquaternary salt germicide | CHINA PETROCHEMICAL CORP (CN) | 2000-05-10 | — | — | CN | disclosed |
| CN-1229588-A | Water insoluble polyquaternary phosphonium salt type germicide | CHINA PETROCHEMICAL CORP (CN) | 1999-09-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210285072-A1 | COUNTERCURRENT RARE EARTH SEPARATION PROCESS | COIL, NAF1, SRSF9 | OPRM1 3796/4885DNM1 628/4885ALDH1A1 4632/4885 |
| US-11958754-B2 | Enhanced separation of rare earth metals | CA2, CA7, SLC39A14 | OPRM1 4009/4885DNM1 1565/4885ALDH1A1 4820/4885 |
| US-12024756-B2 | Countercurrent rare earth separation process | COIL, NAF1, SRSF9 | OPRM1 3796/4885DNM1 628/4885ALDH1A1 4632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.