Trolamine

Trolamine

SCHEMBL21591942

Cc1ccccc1.N.N.OCCN(CCO)CCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
LMNA P02545 2/20 0.50
ALOX12 P18054 1/20 0.50
ACHE P22303 1/20 0.50
KDM4E B2RXH2 4/20 0.42
HTT P42858 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP2C19 P33261 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
ALOX15 P16050 1/20 0.39
SCN1A P35498 1/20 0.39
HIF1A Q16665 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
HSD17B10 Q99714 2/20 0.38
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL28095828 0.98 TSHR (0.52) TSHRLMNAALOX12ACHEKDM4E
Trolamine SCHEMBL28203215 0.81 TSHR (0.50) TSHRLMNAACHEKDM4EHTT
Toluene SCHEMBL409208 0.80 ACHE (0.69) TSHRLMNAALOX12ACHEKDM4E
Trolamine SCHEMBL28412671 0.77 ACHE (0.59) LMNAACHEKDM4EHTTMEN1
Trolamine SCHEMBL27761516 0.77 KDM4E (0.40) TSHRLMNAKDM4EHTTMEN1
Trolamine SCHEMBL3893278 0.76 TDP1 (0.55) LMNAKDM4EHTTMEN1KMT2A
Toluene SCHEMBL906170 0.75 LMNA (0.61) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL11300497 0.75 LMNA (0.61) TSHRLMNAALOX12ACHEHTT
Toluene SCHEMBL11669463 0.75 TSHR (0.61) TSHRLMNAALOX12ACHEKDM4E
Toluene SCHEMBL5198578 0.75 ACHE (0.69) TSHRLMNAALOX12ACHEHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108976463-B Composition set for preparing polyurethane foam, preparation method and application thereof 合肥华凌股份有限公司 2021-01-26 CN disclosed
WO-2019237728-A1 COMPOSITION KIT FOR PREPARING POLYURETHANE FOAM AND PREPARATION METHOD AND APPLICATION THEREOF 合肥华凌股份有限公司 2019-12-19 WO disclosed