Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267470 | 0.85 | ALDH1A1 (0.62) | HPGDHTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3688021 | 0.85 | ALDH1A1 (0.62) | HPGDHTTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28472071 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL2159413 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL6065093 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL5674958 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL5674983 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL5678437 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL5679165 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 | |
| SCHEMBL5674974 | 0.84 | NAAA (0.70) | HPGDHTTALDH1A1KDM4EHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089515-B2 | Long chain N-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY (US) | 2015-07-28 | — | — | US | disclosed |
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2011-07-28 | — | — | US | disclosed |
| US-7816560-B1 | Long chain n-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY (US) | 2010-10-19 | — | — | US | disclosed |
| US-20100137365-A1 | Long chain N-alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2010-06-03 | — | — | US | disclosed |
| EP-1210082-B1 | LONG CHAIN N-ALKYL COMPOUNDS AND OXA-DERIVATIVES THEREOF AND USE AS ANTIVIRAL COMPOSITIONS | UNIV OXFORD (GB) | 2008-01-02 | — | — | EP | disclosed |
| EP-1210082-A2 | LONG CHAIN N-ALKYL COMPOUNDS AND OXA-DERIVATIVES THEREOF AND USE AS ANTIVIRAL COMPOSITIONS | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001010429-A2 | LONG CHAIN N-ALKYL COMPOUNDS AND OXA-DERIVATIVES THEREOF AND USE AS ANTIVIRAL COMPOSITIONS | THE CHANCELLOR, MASTERS, AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2001-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137365-A1 | Long chain N-alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | HPGD 1500/4885HTT 1700/4885ALDH1A1 1474/4885 |
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | HPGD 1500/4885HTT 1700/4885ALDH1A1 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.