Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 1.00 |
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | MMP1 | P03956 | 1/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 1/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | NAMPT | P43490 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180694 | 1.00 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AEGFR | |
| SCHEMBL18407399 | 0.86 | RAB9A (0.76) | RAB9ANPC1MEN1KMT2AEGFR | |
| SCHEMBL30098435 | 0.85 | NPC1 (0.74) | RAB9ANPC1MEN1KMT2AEGFR | |
| SCHEMBL23924135 | 0.85 | NPC1 (0.74) | RAB9ANPC1MEN1KMT2AEGFR | |
| SCHEMBL4987866 | 0.84 | NPC1 (0.73) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL13675635 | 0.84 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| N-Phenylcinnamamide SCHEMBL4205896 | 0.84 | MMP1 (1.00) | RAB9ANPC1MEN1KMT2AEGFR | |
| N-Phenylcinnamamide SCHEMBL2682029 | 0.84 | MMP1 (1.00) | RAB9ANPC1MEN1KMT2AEGFR | |
| N-Phenylcinnamamide SCHEMBL3667414 | 0.84 | MMP1 (1.00) | RAB9ANPC1MEN1KMT2AEGFR | |
| SCHEMBL22645461 | 0.83 | NPC1 (0.70) | RAB9ANPC1MEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210207175-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2021-07-08 | — | — | US | disclosed |
| WO-2019238091-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210207175-A1 | COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF | TET2, ZFX, ZFR | RAB9A 3127/4885NPC1 156/4885MEN1 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.