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Sugi Predict / Targets / PLAAT5

PLAAT5

Phospholipase A and acyltransferase 5 · Q96KN8 · PLAAT5 on Sugi Atlas →

11,047 patent compounds predicted against PLAAT5, 7,511 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL26657 SCHEMBL26657 0.53 10/20
SCHEMBL1027805 SCHEMBL1027805 0.64 7/20
SCHEMBL1622156 SCHEMBL1622156 0.50 6/20
SCHEMBL710419 SCHEMBL710419 0.62 5/20
SCHEMBL694045 SCHEMBL694045 0.58 4/20
SCHEMBL660787 SCHEMBL660787 0.56 4/20
SCHEMBL991969 SCHEMBL991969 0.56 4/20
SCHEMBL553140 SCHEMBL553140 0.50 4/20
SCHEMBL442914 SCHEMBL442914 0.46 4/20
SCHEMBL1645537 SCHEMBL1645537 0.44 4/20
Phenethylcarbamic Acid Phenethylcarbamic Acid (SCHEMBL249525) 0.63 3/20
SCHEMBL1567251 SCHEMBL1567251 0.61 3/20
SCHEMBL159162 SCHEMBL159162 0.59 3/20
SCHEMBL426275 SCHEMBL426275 0.59 3/20
SCHEMBL1756655 SCHEMBL1756655 0.59 3/20
SCHEMBL440625 SCHEMBL440625 0.57 3/20
SCHEMBL1776 SCHEMBL1776 0.56 3/20
SCHEMBL1681600 SCHEMBL1681600 0.54 3/20
SCHEMBL659686 SCHEMBL659686 0.54 3/20
SCHEMBL349314 SCHEMBL349314 0.53 3/20

Clinical trials — most relevant to PLAAT5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Omega-3 Fatty Acids on the Human Gene Expression PHASE4COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
GSK2190915A - Bioavailability Study PHASE1COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Insulin Regulation of Lipolysis and Lipolysis Proteins EARLY_PHASE1RECRUITING
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Heart & Health Study nanCOMPLETED
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity. nanCOMPLETED
Genetic Markers of CHD Risk in Men and Women nanCOMPLETED
Choline to Improve Malnutrition and Enhance Cognition nanRECRUITING
Genetic and Environmental Determinants of Triglycerides (GOLDN) nanCOMPLETED
Genetical Background of Non-alcoholic Fatty Liver Disease (NAFLD) in Diabetes Mellitus and in Chronic Kidney Disease nanUNKNOWN
A 12 Week, 3-Period Study to Evaluate the Effects of a Dietary Supplement on Lipid Metabolism nanCOMPLETED
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children nanWITHDRAWN
Gene Expression in Obesity and Insulin Resistance nanCOMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
for Adipose Tissue DIabetes VAriants (fATDIVA) nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Genomic Dissection of a QTL Affecting the Lipid Profile nanWITHDRAWN
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
Dietary Fatty Acids, PPAR Activated Genes, and CHD nanCOMPLETED
Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo nanCOMPLETED
Canola Oil Multicentre Intervention Trial nanCOMPLETED
Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke nanCOMPLETED
Molecular Markers of Human Sperm Function nanWITHDRAWN
Lipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects) nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PLAAT5 binder may also engage these)

ProteinNameSimilarity
Q4KLN5 — 0.997 Q4KLN5 →
Q9CPX5 — 0.991 Q9CPX5 →
Q8WY91 — 0.965 Q8WY91 →
Q8N2C3 — 0.965 Q8N2C3 →
Q9D650 — 0.963 Q9D650 →
Q9P2E8 — 0.961 Q9P2E8 →
Q80TL0 — 0.961 Q80TL0 →
Q93075 — 0.960 Q93075 →
Q642B6 — 0.960 Q642B6 →
Q5VUJ9 — 0.960 Q5VUJ9 →
Q14679 — 0.960 Q14679 →
A2AGX3 — 0.960 A2AGX3 →
O88884 — 0.960 O88884 →
Q96KN4 — 0.960 Q96KN4 →
Q6P3Z3 — 0.960 Q6P3Z3 →
Q92667 — 0.959 Q92667 →
Q7TN83 — 0.959 Q7TN83 →
Q4V7B1 — 0.959 Q4V7B1 →
Q80Z30 — 0.958 Q80Z30 →
O08715 — 0.958 O08715 →
Q9NQV5 — 0.958 Q9NQV5 →
Q8NFT6 — 0.958 Q8NFT6 →
D4A7U2 — 0.958 D4A7U2 →
Q8K451 — 0.958 Q8K451 →
Q8NE31 — 0.958 Q8NE31 →
Q5SYB0 — 0.958 Q5SYB0 →
Q8WY54 — 0.958 Q8WY54 →
Q5VTJ3 — 0.958 Q5VTJ3 →
Q9BZ19 — 0.957 Q9BZ19 →
Q9BWG6 — 0.957 Q9BWG6 →