Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 18/20 | 0.88 |
| ▸ | NSD2 | O96028 | 3/20 | 0.88 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.88 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.88 |
| ▸ | NPC1 | O15118 | 1/20 | 0.88 |
| ▸ | KDM1A | O60341 | 1/20 | 0.88 |
| ▸ | MTOR | P42345 | 1/20 | 0.88 |
| ▸ | RAB9A | P51151 | 1/20 | 0.88 |
| ▸ | DNMT3A | Q9Y6K1 | 2/20 | 0.82 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351415 | 0.94 | EHMT2 (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| SCHEMBL366593 | 0.94 | EHMT2 (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| Water SCHEMBL21610936 | 0.93 | EHMT2 (0.98) | EHMT2NSD2NSD3EHMT1NPC1 | |
| Hydrochloric Acid SCHEMBL29849313 | 0.93 | EHMT2 (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| Hydrochloric Acid SCHEMBL2595237 | 0.93 | EHMT2 (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| Hydrochloric Acid SCHEMBL20535174 | 0.93 | EHMT2 (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| Hydrochloric Acid SCHEMBL15668608 | 0.92 | EHMT2 (0.98) | EHMT2NSD2NSD3EHMT1NPC1 | |
| SCHEMBL18095978 | 0.90 | DNMT3A (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| SCHEMBL14940754 | 0.90 | EHMT2 (1.00) | EHMT2NSD2NSD3EHMT1NPC1 | |
| SCHEMBL7982595 | 0.90 | EHMT2 (0.86) | EHMT2NSD2NSD3EHMT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238817-A1 | BIFUNCTIONAL MOLECULES FOR TARGETING RPN11 | UNIVERSITY OF DUNDEE (GB) | 2019-12-19 | — | — | WO | disclosed |
| WO-2019238816-A1 | BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 | UNIVERSITY OF DUNDEE (GB) | 2019-12-19 | — | — | WO | disclosed |