SCHEMBL2159395

SCHEMBL2159395

C=CCN(CCCCC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.46
ZDHHC2 Q9UIJ5 2/20 0.46
ALDH1A1 P00352 2/20 0.44
FAAH O00519 1/20 0.41
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA9 Q16790 3/20 0.39
CA2 P00918 1/20 0.38
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP8 P22894 1/20 0.37
TSHR P16473 2/20 0.37
AKR1B1 P15121 1/20 0.35
MGLL Q99685 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11264305 0.96 ZDHHC20 (0.47) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL2044848 0.88 ALDH1A1 (0.50) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL2159389 0.85 ZDHHC20 (0.46) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL2362353 0.85 ZDHHC20 (0.46) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL29333 0.83 ZDHHC20 (0.45) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL3259264 0.83 ZDHHC20 (0.45) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL1076719 0.83 ZDHHC20 (0.61) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL8033183 0.83 ALDH1A1 (0.47) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL20274383 0.81 ZDHHC20 (0.64) ZDHHC20ZDHHC2ALDH1A1FAAHCA12
SCHEMBL11085445 0.81 ZDHHC20 (0.47) ZDHHC20ZDHHC2ALDH1A1FAAHCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7815724-B2 Ink composition FUJIFILM CORPORATION (JP) 2010-10-19 US claimed
EP-1343807-B1 DIARYL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITS C VIRUS SCHERING CORP (US) 2009-04-29 EP claimed
EP-1268525-B1 MACROCYCLIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS COMPRISING N-CYCLIC P2 MOIETIES SCHERING CORP (US) 2008-12-31 EP claimed
US-20050090486-A1 Trisubstituted pyrimidines BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-04-28 US claimed
CN-1501942-A Diaryl peptides as ns3-serine protease inhibitors of hepatitis c virus ���鹫˾ 2004-06-02 CN claimed
CN-1441806-A Macrocyclic NS 3-serine protease inhibitors of hepatitis C virus comprising an N-ring P2 moiety SCHERING CORP (US) 2003-09-10 CN claimed
US-20030134838-A1 Trisubstituted pyrimidines BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-17 US claimed
WO-2001022821-A1 INSECTICIDE COMPOSITIONS OF A CARBAMATE WITH A PYRAZOLE, PYRROLE OR PHENYLIMIDAZOLE AVENTIS CROPSCIENCE S.A. (FR) 2001-04-05 WO claimed
EP-0000895-A1 Aryl-N-alkylcarbamates, method for their preparation and their use as insecticides BAYER AG (DE) 1979-03-07 EP claimed
EP-1502941-B1 Image-forming method and developer FUJIFILM CORP (JP) 2015-12-23 EP disclosed
CN-102199468-B Lubricant composition for improving engine performance AFTON CHEMICAL CORP 2014-06-25 CN disclosed
EP-1762894-B1 Photopolymerizable photosensitive lithographic printing plate FUJIFILM CORP (JP) 2013-01-09 EP disclosed
CN-101315522-B Photosensitive composition, photosensitive film, and printed circuit board FUJI PHOTO FILM CO LTD 2012-08-29 CN disclosed
CN-101438210-B Photosensitive composition, photosensitive film, photosensitive laminate, method of forming permanent pattern and printed board FUJI PHOTO FILM CO LTD 2012-06-20 CN disclosed
EP-0373573-A1 Recording material for ink jet printing CIBA-GEIGY AG (CH) 1990-06-20 EP disclosed
EP-0208921-A2 Hydroformylation of olefinic compounds in the presence of soluble cobalt salt catalysts and an organic nitrile promoter HENKEL CORPORATION (a Delaware corp.) (US) 1987-01-21 EP disclosed
US-4612403-A Hydroformylation of olefinic compounds in the presence of a cobalt catalyst and an organic nitrile promoter HENKEL CORPORATION (US) 1986-09-16 US disclosed
EP-0000895-A1 Aryl-N-alkylcarbamates, method for their preparation and their use as insecticides BAYER AG (DE) 1979-03-07 EP disclosed
EP-0000895-A1 Aryl-N-alkylcarbamates, method for their preparation and their use as insecticides BAYER AG (DE) 1979-03-07 EP disclosed
EP-0000895-A1 Aryl-N-alkylcarbamates, method for their preparation and their use as insecticides BAYER AG (DE) 1979-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030134838-A1 Trisubstituted pyrimidines APP, PSEN1, BACE1 ZDHHC20 2378/4885ZDHHC2 2898/4885ALDH1A1 753/4885
US-20050090486-A1 Trisubstituted pyrimidines APP, BACE1, PSEN1 ZDHHC20 2739/4885ZDHHC2 3582/4885ALDH1A1 681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.