Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 8/20 | 0.41 |
| ▸ | TOP1 | P11387 | 5/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671002 | 0.83 | TOP1 (0.47) | KDM4EKMT2AADRA2BMAPK1AADAT | |
| SCHEMBL10330763 | 0.81 | KDM4E (0.47) | KDM4EKMT2AADRA2BMAPK1AADAT | |
| SCHEMBL9872072 | 0.80 | KDM4E (0.63) | KDM4EKMT2AAADATALDH1A1HPGD | |
| SCHEMBL9872260 | 0.79 | KDM4E (0.62) | KDM4EKMT2AAADATTOP2ATOP1 | |
| Pazufloxacin SCHEMBL8386358 | 0.78 | KDM4E (1.00) | KDM4EKMT2AAADATALDH1A1HPGD | |
| Pazufloxacin SCHEMBL21074686 | 0.78 | KDM4E (1.00) | KDM4EKMT2AAADATALDH1A1HPGD | |
| Pazufloxacin SCHEMBL34460 | 0.78 | KDM4E (1.00) | KDM4EKMT2AAADATALDH1A1HPGD | |
| Bromide SCHEMBL9875030 | 0.78 | KDM4E (0.61) | KDM4EKMT2AAADATTOP2ATOP1 | |
| Pazufloxacin SCHEMBL29381001 | 0.78 | KDM4E (1.00) | KDM4EKMT2AAADATALDH1A1HPGD | |
| Pazufloxacin SCHEMBL9872951 | 0.78 | KDM4E (0.98) | KDM4EKMT2AAADATALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019238057-A1 | APPLICATION OF FSO2N3 IN PREPARATION OF AZIDE | 中国科学院上海有机化学研究所 | 2019-12-19 | — | — | WO | disclosed |