Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TOP1 | P11387 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 9/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185781 | 0.86 | KDM4E (0.45) | KDM4EKMT2ATOP1GSK3BAADAT | |
| SCHEMBL1185901 | 0.82 | GSK3B (0.47) | KDM4EKMT2ATOP1GSK3BAADAT | |
| SCHEMBL8090221 | 0.82 | GSK3B (0.47) | KDM4EKMT2ATOP1GSK3BAADAT | |
| SCHEMBL21594482 | 0.80 | KDM4E (0.64) | KDM4EKMT2ATOP1AADATTOP2A | |
| SCHEMBL9872260 | 0.78 | KDM4E (0.62) | KDM4EKMT2ATOP1AADATTOP2A | |
| Pazufloxacin SCHEMBL21074686 | 0.78 | KDM4E (1.00) | KDM4EKMT2AGSK3BAADATTOP2A | |
| Pazufloxacin SCHEMBL29381001 | 0.78 | KDM4E (1.00) | KDM4EKMT2AGSK3BAADATTOP2A | |
| Pazufloxacin SCHEMBL34460 | 0.78 | KDM4E (1.00) | KDM4EKMT2AGSK3BAADATTOP2A | |
| Bromide SCHEMBL9875030 | 0.78 | KDM4E (0.61) | KDM4EKMT2ATOP1AADATTOP2A | |
| Pazufloxacin SCHEMBL8386358 | 0.78 | KDM4E (1.00) | KDM4EKMT2AGSK3BAADATTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | claimed |