Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21595525 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPTALDH1A1ALOX15GAA | |
| SCHEMBL21595541 | 0.84 | KDM4E (0.44) | SMN1; SMN2MAPTALDH1A1GAANPC1 | |
| SCHEMBL21595540 | 0.84 | KDM4E (0.44) | SMN1; SMN2MAPTALDH1A1GAANPC1 | |
| SCHEMBL20302204 | 0.81 | P2RX7 (0.33) | NPC1RAB9ATBXA2RHTTPKM | |
| SCHEMBL20302205 | 0.81 | P2RX7 (0.33) | NPC1RAB9ATBXA2RHTTPKM | |
| SCHEMBL21595505 | 0.74 | HSP90AA1 (0.43) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL21595503 | 0.74 | HSP90AA1 (0.43) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL21595506 | 0.73 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL21595504 | 0.73 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL21595495 | 0.73 | RAB9A (0.35) | SMN1; SMN2MAPTALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810597-B1 | 1,2,4-TRIAZOLE DERIVATIVES AS TANKYRASE INHIBITORS | UNIV OSLO HF (NO) | 2025-11-26 | — | — | EP | disclosed |
| US-11926614-B2 | 1,2,4-triazole derivatives as tankyrase inhibitors | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2024-03-12 | — | — | US | disclosed |
| EP-3810597-A1 | 1,2,4-TRIAZOLE DERIVATIVES AS TANKYRASE INHIBITORS | Oslo Universitetssykehus HF (NO) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243822-A1 | 1,2,4-TRIAZOLE DERIVATIVES AS TANKYRASE INHIBITORS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11926614-B2 | 1,2,4-triazole derivatives as tankyrase inhibitors | GBA3, CBR3, TECR | SMN1; SMN2 4006/4885MAPT 3627/4885ALDH1A1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.