SCHEMBL21596688

COc1ccc(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)c(OCC(F)F)n1.COc1nc(OC(F)F)c(F)cc1NS(=O)(=O)c1c[nH]c2nc(C(F)F)ccc12.COc1nc(OCC(F)F)ccc1NS(=O)(=O)c1c[nH]c2cc(Cl)ccc12

nearest known ligand 0.34

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	CYP2C9	P11712	2/20	0.34

▸	EIF2AK4	Q9P2K8	2/20	0.30

▸	CYP2C19	P33261	1/20	0.30

▸	SGK1	O00141	1/20	0.30

▸	CYP3A4	P08684	1/20	0.30

▸	EIF2AK3	Q9NZJ5	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29829681	0.84	MEN1 (0.37)	CYP2C9EIF2AK4SGK1CYP3A4EIF2AK3
SCHEMBL23610290	0.84	MEN1 (0.37)	CYP2C9EIF2AK4SGK1CYP3A4EIF2AK3
SCHEMBL29830572	0.84	MEN1 (0.37)	EIF2AK4SGK1CYP3A4EIF2AK3
SCHEMBL23610286	0.84	MEN1 (0.37)	EIF2AK4SGK1CYP3A4EIF2AK3
SCHEMBL29829927	0.83	SLC40A1 (0.38)	CYP2C9EIF2AK4CYP2C19SGK1CYP3A4
SCHEMBL21596699	0.83	SLC40A1 (0.38)	CYP2C9EIF2AK4CYP2C19SGK1CYP3A4
SCHEMBL21596662	0.82	CYP2C9 (0.34)	CYP2C9CYP2C19CYP3A4
SCHEMBL29829592	0.82	CYP2C9 (0.34)	CYP2C9CYP2C19CYP3A4
SCHEMBL21596678	0.82	SCN9A (0.33)	CYP2C9
SCHEMBL21596690	0.82	SGK1 (0.39)	CYP2C9EIF2AK4CYP2C19SGK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3810591-A1	PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES	UCB Pharma GmbH (DE)	2021-04-28	—	—	EP	disclosed
WO-2019243303-A1	PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES	UCB PHARMA GMBH (DE)	2019-12-26	—	—	WO	disclosed