Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 2/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610290 | 1.00 | MEN1 (0.37) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL23610286 | 0.93 | MEN1 (0.37) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL29830572 | 0.93 | MEN1 (0.37) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL23620321 | 0.88 | PRKAG1 (0.42) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL30991309 | 0.88 | PRKAG1 (0.42) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL29829927 | 0.85 | SLC40A1 (0.38) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL21596699 | 0.85 | SLC40A1 (0.38) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL21596688 | 0.84 | CYP2C9 (0.34) | SGK1EIF2AK4CYP3A4EIF2AK3CYP2C9 | |
| SCHEMBL30684707 | 0.83 | CCR4 (0.37) | MEN1KMT2ACCR4NR4A2SGK1 | |
| SCHEMBL27037080 | 0.83 | CCR4 (0.37) | MEN1KMT2ACCR4NR4A2SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | claimed |
| EP-3810591-B1 | PYRIDINYL AND PYRAZINYL-(AZA)INDOLSULFONAMIDES | UCB PHARMA GMBH (DE) | 2022-08-10 | — | — | EP | claimed |
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |