SCHEMBL2159678

SCHEMBL2159678

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nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2190171 0.94 ALDH1A1 (0.60) ALDH1A1
SCHEMBL16267467 0.92 ALDH1A1 (0.58) ALDH1A1
SCHEMBL5576032 0.84 ALDH1A1 (0.46) ALDH1A1
SCHEMBL1395028 0.82
SCHEMBL8572734 0.79 ALDH1A1 (0.58) ALDH1A1
SCHEMBL1538354 0.75 ALDH1A1 (0.38) ALDH1A1
SCHEMBL27477758 0.75 ALDH1A1 (0.52) ALDH1A1
SCHEMBL27724962 0.73 ALDH1A1 (0.55) ALDH1A1
SCHEMBL2576139 0.72 ALDH1A1 (0.43) ALDH1A1
SCHEMBL4187087 0.71 ALDH1A1 (0.52) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110183034-A1 ENHANCEMENT OF MAGENESIUM UPTAKE IN MAMMALS JAFFE RUSSELL 2011-07-28 US claimed
EP-1660103-A4 ENHANCEMENT OF MAGNESIUM UPTAKE IN MAMMALS PERQUE INC (US) 2009-07-08 EP claimed
JP-2007533609-A 2007-11-22 JP claimed
EP-1660103-A2 ENHANCEMENT OF MAGNESIUM UPTAKE IN MAMMALS Perque, Inc. (US) 2006-05-31 EP claimed
WO-2005018550-A2 ENHANCEMENT OF MAGNESIUM UPTAKE IN MAMMALS PERQUE, INC. (US) 2005-03-03 WO claimed
US-20050037998-A1 Enhancement of magnesium uptake in mammals RMJ160 LLC 2005-02-17 US claimed
EP-2606900-A1 Enhancement of magnesium uptake in mammals Perque, Inc. (US) 2013-06-26 EP disclosed