SCHEMBL5576032

SCHEMBL5576032

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nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8572734 0.94 ALDH1A1 (0.58) ALDH1A1
SCHEMBL1538354 0.89 ALDH1A1 (0.38) ALDH1A1
SCHEMBL28317591 0.88 ALDH1A1 (0.36) ALDH1A1
Ethylene Glycol SCHEMBL907989 0.85 TSHR (0.35) ALDH1A1
SCHEMBL2159678 0.84 ALDH1A1 (0.48) ALDH1A1
SCHEMBL8603898 0.83
SCHEMBL5576028 0.80 ALDH1A1 (0.40) ALDH1A1
SCHEMBL2190171 0.79 ALDH1A1 (0.60) ALDH1A1
SCHEMBL2576139 0.79 ALDH1A1 (0.43) ALDH1A1
SCHEMBL16267467 0.78 ALDH1A1 (0.58) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10391060-B2 Particulate delivery systems RUBICON RESEARCH PRIVATE LIMITED (IN) 2019-08-27 US claimed
US-20190000763-A1 PARTICULATE DELIVERY SYSTEMS RUBICON RESEARCH PRIVATE LIMITED (IN) 2019-01-03 US claimed
US-20070009441-A1 Biodegradable nanoparticles MOLECULAR THERAPEUTICS, INC. (US) 2007-01-11 US claimed
WO-2006010083-A2 BIODEGRADABLE NANOPARTICLES MOLECULAR THERAPEUTICS, INC. (US) 2006-01-26 WO claimed
WO-2005089106-A2 DEGRADABLE NANOPARTICLES MOLECULAR THERAPEUTICS, INC. (US) 2005-09-29 WO claimed
US-20050196343-A1 Polyacrylamide backbone; drug delivery, imaging, diagnosis; easily eliminated by body MOLECULAR THERAPEUTICS, INC. (US) 2005-09-08 US claimed
US-10391060-B2 Particulate delivery systems RUBICON RESEARCH PRIVATE LIMITED (IN) 2019-08-27 US disclosed
US-20190000763-A1 PARTICULATE DELIVERY SYSTEMS RUBICON RESEARCH PRIVATE LIMITED (IN) 2019-01-03 US disclosed
WO-2017021983-A1 PARTICULATE DELIVERY SYSTEMS RUBICON RESEARCH PRIVATE LIMITED (IN) 2017-02-09 WO disclosed
US-20070009441-A1 Biodegradable nanoparticles MOLECULAR THERAPEUTICS, INC. (US) 2007-01-11 US disclosed
WO-2006010083-A2 BIODEGRADABLE NANOPARTICLES MOLECULAR THERAPEUTICS, INC. (US) 2006-01-26 WO disclosed
WO-2005089106-A2 DEGRADABLE NANOPARTICLES MOLECULAR THERAPEUTICS, INC. (US) 2005-09-29 WO disclosed
US-20050196343-A1 Polyacrylamide backbone; drug delivery, imaging, diagnosis; easily eliminated by body MOLECULAR THERAPEUTICS, INC. (US) 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070009441-A1 Biodegradable nanoparticles CD47, CD63, ECPAS ALDH1A1 551/4885
US-20050196343-A1 Polyacrylamide backbone; drug delivery, imaging, diagnosis; easily eliminated by body ECPAS, ACTB, SERPINB10 ALDH1A1 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.