Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 13/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528828 | 0.79 | TRPV4 (0.47) | TRPV4CYP11B2EGLN2 | |
| SCHEMBL18865611 | 0.77 | NOTUM (0.53) | TRPV4ARCYP11B2 | |
| SCHEMBL22641636 | 0.72 | KMT2A (0.53) | — | |
| SCHEMBL1361513 | 0.71 | AR (0.50) | TRPV4ARCYP11B2 | |
| SCHEMBL4299688 | 0.71 | AR (0.61) | TRPV4ARCYP11B2 | |
| SCHEMBL10063487 | 0.70 | AR (0.60) | TRPV4ARCYP11B2 | |
| SCHEMBL15117196 | 0.70 | AR (0.60) | TRPV4ARCYP11B2 | |
| SCHEMBL7498187 | 0.70 | AR (0.56) | ARCYP11B2 | |
| SCHEMBL3480511 | 0.69 | NOTUM (0.43) | ARCYP11B2 | |
| SCHEMBL6623551 | 0.69 | AR (0.48) | TRPV4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| US-12365655-B2 | Compounds | CTXT PTY LTD (AU) | 2025-07-22 | — | — | US | disclosed |
| CN-112334466-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-4335439-A2 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-03-13 | — | — | EP | disclosed |
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| CN-112334466-A | Compound (I) | CTXT私人有限公司 | 2021-02-05 | — | — | CN | disclosed |
| US-20200039945-A1 | Compounds | CTXT PTY LIMITED (AU) | 2020-02-06 | — | — | US | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153710-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | TRPV4 908/4885AR 1499/4885CYP11B2 6/4885 |
| US-20200039945-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | TRPV4 909/4885AR 1495/4885CYP11B2 6/4885 |
| US-20260062393-A1 | Compounds | SCN2B, ABCB11, SCN1B | TRPV4 1449/4885AR 336/4885CYP11B2 629/4885 |
| US-12365655-B2 | Compounds | SLC10A1, ABCB11, PCSK9 | TRPV4 909/4885AR 1495/4885CYP11B2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.