Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | PKM | P14618 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596859 | 0.79 | TDO2 (0.44) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL29652518 | 0.79 | TDO2 (0.44) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL21596921 | 0.75 | PIK3CD (0.47) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL17427076 | 0.75 | KDM4E (0.57) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL21596913 | 0.73 | CFTR (0.35) | — | |
| SCHEMBL13581443 | 0.73 | KDM4E (0.55) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL30776779 | 0.73 | KDM4E (0.55) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL25395443 | 0.72 | KDM4E (0.47) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL25393293 | 0.72 | KDM4E (0.44) | TDO2NPC1KDM4ERAB9APKM | |
| SCHEMBL23080058 | 0.71 | KDM4E (0.58) | TDO2NPC1KDM4ERAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |