Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21596805 | 0.78 | CFTR (0.36) | CFTRBRD4PIK3CDPIK3CGCSNK1A1 | |
| SCHEMBL29652442 | 0.78 | CFTR (0.36) | CFTRBRD4PIK3CDPIK3CGCSNK1A1 | |
| SCHEMBL21596918 | 0.74 | BRD4 (0.39) | BRD4CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL21596937 | 0.73 | TDO2 (0.47) | — | |
| SCHEMBL4408061 | 0.69 | KDM4E (0.43) | CFTRBRD4PIK3CDPIK3CG | |
| SCHEMBL655701 | 0.67 | BRD4 (0.36) | CFTRBRD4PIK3CDPIK3CG | |
| SCHEMBL5210212 | 0.66 | KDM4E (0.37) | CFTRBRD4PIK3CDPIK3CGCSNK1A1 | |
| SCHEMBL16892132 | 0.66 | BRD4 (0.45) | BRD4 | |
| SCHEMBL1289874 | 0.65 | ALDH1A1 (0.42) | CFTRBRD4PIK3CDPIK3CG | |
| SCHEMBL11017014 | 0.65 | NPC1 (0.46) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |