SCHEMBL215973

SCHEMBL215973

CCCCCC(C)C.N=C=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.44
LMNA P02545 2/20 0.42
CA1 P00915 2/20 0.41
MAPT P10636 1/20 0.40
TP53 P04637 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
FDPS P14324 4/20 0.38
ACE2 Q9BYF1 1/20 0.38
GPR84 Q9NQS5 3/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
SPHK1 Q9NYA1 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11344550 1.00 OPRM1 (0.44) OPRM1LMNACA1MAPTTP53
SCHEMBL27916344 0.98 MAPT (0.43) OPRM1LMNACA1MAPTTP53
SCHEMBL28852259 0.98 MAPT (0.43) OPRM1LMNACA1MAPTTP53
SCHEMBL11407940 0.98 MAPT (0.43) OPRM1LMNACA1MAPTTP53
SCHEMBL4810926 0.92 LMNA (0.38) OPRM1LMNACA1MAPTTP53
SCHEMBL27576249 0.92 LMNA (0.38) OPRM1LMNACA1MAPTTP53
Methane SCHEMBL29039910 0.90 LMNA (0.36) OPRM1LMNACA1MAPTTP53
SCHEMBL11227380 0.89 LMNA (0.50) LMNACA1
SCHEMBL28417881 0.87 LMNA (0.48) LMNACA1MAPT
SCHEMBL1349452 0.85 OPRM1 (0.44) OPRM1LMNACA1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220380303-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2022-12-01 US claimed
CN-114423736-A Method for distilling isocyanates 科思创知识产权两合公司 2022-04-29 CN claimed
WO-2021063760-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-04-08 WO claimed
EP-1717223-B1 Method for the purification of isocyanates BASF SE (DE) 2016-07-20 EP claimed
US-8088944-B2 Method for the purification of isocyanates BASF SE (DE) 2012-01-03 US claimed
US-20070015934-A1 Method for the purification of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 US claimed
US-20240101508-A1 METHOD FOR PREPARING ISOCYANATE COMPOUND Hanwha Solutions Corporation (KR) 2024-03-28 US disclosed
US-20240067602-A1 METHOD FOR PREPARING ISOCYANATE COMPOUND Hanwha Solutions Corporation (KR) 2024-02-29 US disclosed
US-20240067601-A1 METHOD FOR PREPARING ISOCYANATE COMPOUND Hanwha Solutions Corporation (KR) 2024-02-29 US disclosed
EP-4276091-A1 METHOD FOR PREPARING ISOCYANATE COMPOUND Hanwha Solutions Corporation (KR) 2023-11-15 EP disclosed
EP-4273123-A1 METHOD FOR PREPARING ISOCYANATE COMPOUND Hanwha Solutions Corporation (KR) 2023-11-08 EP disclosed
EP-4273122-A1 ISOCYANATE COMPOUND PREPARATION METHOD Hanwha Solutions Corporation (KR) 2023-11-08 EP disclosed
EP-4273121-A1 ISOCYANATE COMPOUND PREPARATION METHOD Hanwha Solutions Corporation (KR) 2023-11-08 EP disclosed
EP-2042485-A1 Process for fractionating a mixture of polyisocyanates HUNTSMAN INTERNATIONAL LLC (US) 2009-04-01 EP disclosed
US-7358388-B2 Method for the purification of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2008-04-15 US disclosed
US-20070232827-A1 Isocyanate Production Method BASF AKTIENGESELLSCHAFT (DE) 2007-10-04 US disclosed
US-20070015934-A1 Method for the purification of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 US disclosed
US-20060135810-A1 Method for the purification of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2006-06-22 US disclosed
US-20060116529-A1 Method for the production of isocyanates BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 US disclosed
CN-1351625-A Condensation polymer containing dialkylamide enalgroups, process for producing said condensation polymers and applications thereof DSM NV (NL) 2002-05-29 CN disclosed