Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22339776 | 0.84 | CA1 (0.33) | CHRNA7 | |
| SCHEMBL16472376 | 0.83 | ACHE (0.39) | ACHEPAX8KDM4EALDH1A1 | |
| SCHEMBL16478638 | 0.83 | ACHE (0.39) | ACHEPAX8KDM4EALDH1A1 | |
| SCHEMBL24634254 | 0.83 | ACHE (0.39) | ACHEPAX8KDM4EALDH1A1 | |
| SCHEMBL28880244 | 0.81 | TP53 (0.38) | ACHEKDM4EALDH1A1CHRNA7 | |
| SCHEMBL23209176 | 0.81 | TP53 (0.38) | ACHEKDM4EALDH1A1CHRNA7 | |
| SCHEMBL2377043 | 0.81 | TP53 (0.38) | ACHEKDM4EALDH1A1CHRNA7 | |
| Hydrochloric Acid SCHEMBL25385046 | 0.79 | TP53 (0.37) | ACHEKDM4EALDH1A1CHRNA7 | |
| SCHEMBL22339772 | 0.77 | — | — | |
| SCHEMBL31756276 | 0.76 | TDO2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810606-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2021-04-28 | — | — | EP | disclosed |
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |