Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 2/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597570 | 0.94 | EPHX2 (0.51) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL21577602 | 0.81 | STS (0.49) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL18986384 | 0.80 | MEN1 (0.49) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL4732973 | 0.80 | EPHX2 (0.61) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL20220390 | 0.80 | EPHX2 (0.56) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL28610512 | 0.80 | STS (0.56) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL21577641 | 0.79 | EPHX2 (0.57) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL30706890 | 0.78 | STS (0.52) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL30642290 | 0.78 | STS (0.51) | EPHX2STSGPR119ALDH1A1MEN1 | |
| SCHEMBL29253172 | 0.77 | STS (0.58) | EPHX2STSGPR119ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810606-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |