Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CTSE | P14091 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP7 | P09237 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732973 | 0.84 | EPHX2 (0.61) | STSEPHX2ALDH1A1TGFBR1MAPT | |
| SCHEMBL21577641 | 0.83 | EPHX2 (0.57) | STSEPHX2ALDH1A1TGFBR1MAPT | |
| SCHEMBL29253075 | 0.82 | APLNR (0.49) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL28970355 | 0.82 | APLNR (0.56) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29253093 | 0.80 | ALDH1A1 (0.50) | EPHX2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30706890 | 0.80 | STS (0.52) | STSEPHX2ALDH1A1MAPTBACE1 | |
| SCHEMBL28611807 | 0.80 | ALDH1A1 (0.54) | STSEPHX2ALDH1A1MAPTMEN1 | |
| SCHEMBL27415157 | 0.80 | ALDH1A1 (0.54) | STSEPHX2ALDH1A1MAPTMEN1 | |
| SCHEMBL29083430 | 0.80 | TSHR (0.56) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14851617 | 0.79 | EPHX2 (0.53) | STSEPHX2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290330-A | Amide derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2024-07-05 | — | — | CN | disclosed |