Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21597765 | 0.94 | EPHX2 (0.55) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL28611806 | 0.81 | STS (0.52) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL28622743 | 0.81 | STS (0.52) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL27415157 | 0.79 | ALDH1A1 (0.54) | EPHX2STSALDH1A1KMT2AMEN1 | |
| SCHEMBL28611807 | 0.79 | ALDH1A1 (0.54) | EPHX2STSALDH1A1KMT2AMEN1 | |
| SCHEMBL21577602 | 0.78 | STS (0.49) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL18986384 | 0.77 | MEN1 (0.49) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL20220390 | 0.76 | EPHX2 (0.56) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL4732973 | 0.76 | EPHX2 (0.61) | EPHX2STSGPR119ALDH1A1KMT2A | |
| SCHEMBL31649063 | 0.76 | BMP1 (0.44) | EPHX2STSGPR119ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810606-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243550-A1 | THIOPHENE DERIVATIVES FOR THE TREATMENT OF DISORDERS CAUSED BY IGE | UCB Biopharma SRL (BE) | 2019-12-26 | — | — | WO | disclosed |