SCHEMBL21597879

SCHEMBL21597879

CN(CCN(CCOCCO[Si](C)(C)C(C)(C)C)C(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.33
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17567264 0.88 DUT (0.35) GBA1DUT
SCHEMBL25180272 0.82 CA14 (0.35) GBA1
SCHEMBL22288700 0.82 CA14 (0.33) GBA1
SCHEMBL25453615 0.82 GBA1 (0.32) GBA1
SCHEMBL1968456 0.80 PDK2 (0.36) GBA1
SCHEMBL13272547 0.79 DUT (0.35) DUT
SCHEMBL17555693 0.79 DUT (0.37) DUT
SCHEMBL24192721 0.78 GBA1 (0.35) GBA1
SCHEMBL3052574 0.77 GBA1 (0.34) GBA1DUT
SCHEMBL21597880 0.75 FPR3 (0.31) GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019243825-A1 SMALL MOLECULE MODULATORS OF HUMAN STING, CONJUGATES AND THERAPEUTIC APPLICATIONS CURADEV PHARMA LIMITED (GB) 2019-12-26 WO disclosed