Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979590 | 0.82 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL5913235 | 0.81 | EPHX2 (0.52) | EPHX2NR1H4NPC1MTORSMN1; SMN2 | |
| SCHEMBL7850276 | 0.81 | RIPK1 (0.49) | EPHX2NR1H4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15013037 | 0.81 | SMN1; SMN2 (0.56) | EPHX2NR1H4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30471275 | 0.80 | RIPK1 (0.61) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL4765237 | 0.80 | RIPK1 (0.61) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3765919 | 0.80 | CA12 (0.59) | NPC1RAB9ASMN1; SMN2MEN1TP53 | |
| SCHEMBL1435285 | 0.79 | KMT2A (0.61) | EPHX2NR1H4MEN1KMT2AALDH1A1 | |
| SCHEMBL506307 | 0.79 | MTOR (0.54) | EPHX2NR1H4MTORSMN1; SMN2POLB | |
| SCHEMBL2054822 | 0.79 | EPHX2 (0.50) | EPHX2NR1H4SMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019243825-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING, CONJUGATES AND THERAPEUTIC APPLICATIONS | CURADEV PHARMA LIMITED (GB) | 2019-12-26 | — | — | WO | disclosed |