Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 16/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165128 | 0.82 | L3MBTL1 (0.48) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL3165118 | 0.82 | L3MBTL1 (0.48) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL6192906 | 0.76 | APP (0.43) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL6192897 | 0.76 | APP (0.43) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL3165886 | 0.74 | L3MBTL1 (0.41) | IDH1L3MBTL1 | |
| SCHEMBL3165880 | 0.74 | L3MBTL1 (0.41) | IDH1L3MBTL1 | |
| SCHEMBL26300944 | 0.73 | L3MBTL1 (0.43) | IDH1L3MBTL1 | |
| SCHEMBL3175956 | 0.73 | ACHE (0.41) | IDH1L3MBTL1 | |
| SCHEMBL3175970 | 0.73 | ACHE (0.41) | IDH1L3MBTL1 | |
| SCHEMBL3165129 | 0.73 | HDAC3 (0.44) | CYP2C9CYP2C19IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202766-B1 | ISOXAZOLE DERIVATIVE AS MUTATED ISOCITRATE DEHYDROGENASE 1 INHIBITOR | DAIICHI SANKYO CO LTD (JP) | 2019-12-25 | — | — | EP | disclosed |