Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261331 | 0.83 | FAAH (0.65) | FAAHDNM1CASP2LPAR1NAAA | |
| SCHEMBL1630120 | 0.82 | FAAH (0.73) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL21600753 | 0.81 | TSHR (0.43) | FAAHDNM1CASP2LPAR1NAAA | |
| SCHEMBL20048669 | 0.81 | FAAH (0.58) | FAAHDNM1CASP2LPAR1NAAA | |
| SCHEMBL12360830 | 0.81 | FAAH (0.62) | FAAHDNM1CASP2LPAR1NAAA | |
| SCHEMBL5505706 | 0.81 | FAAH (0.58) | FAAHDNM1CASP2LPAR1NAAA | |
| SCHEMBL23394528 | 0.81 | SLC6A5 (0.54) | FAAHDNM1CASP2LPAR1SLC6A5 | |
| SCHEMBL21600771 | 0.80 | FAAH (0.36) | FAAHDNM1LPAR1EPHX2 | |
| SCHEMBL5500554 | 0.80 | FAAH (0.61) | FAAHDNM1CASP2LPAR1NAAA | |
| SCHEMBL25008200 | 0.80 | FAAH (0.77) | FAAHDNM1CASP2NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019241851-A1 | INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2019-12-26 | — | — | WO | disclosed |