Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21600763 | 0.83 | FAAH (0.38) | MEN1KMT2AFAAHCA1CA2 | |
| SCHEMBL21600762 | 0.81 | RECQL (0.41) | MEN1KMT2AFAAHCA1CA2 | |
| SCHEMBL21600732 | 0.77 | CA1 (0.38) | CA1CA2HDAC6HDAC3HDAC1 | |
| SCHEMBL21600774 | 0.76 | TSHR (0.40) | CA1CA2CA12CA4CA5A | |
| SCHEMBL16490058 | 0.71 | CTSD (0.48) | FAAHCA1CA2HDAC6HDAC3 | |
| SCHEMBL10962384 | 0.71 | OR51E2 (0.56) | MEN1KMT2AHDAC6HDAC3HDAC1 | |
| SCHEMBL10960960 | 0.71 | OR51E2 (0.56) | MEN1KMT2AHDAC6HDAC3HDAC1 | |
| SCHEMBL10961559 | 0.71 | OR51E2 (0.56) | MEN1KMT2AHDAC6HDAC3HDAC1 | |
| SCHEMBL10964715 | 0.71 | OR51E2 (0.56) | MEN1KMT2AHDAC6HDAC3HDAC1 | |
| SCHEMBL10958653 | 0.71 | OR51E2 (0.56) | MEN1KMT2AHDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019241851-A1 | INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2019-12-26 | — | — | WO | disclosed |