Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.55 |
| ▸ | CCNK | O75909 | 2/20 | 0.52 |
| ▸ | CCND3 | P30281 | 2/20 | 0.52 |
| ▸ | CDK9 | P50750 | 2/20 | 0.52 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.52 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 3/20 | 0.49 |
| ▸ | INSR | P06213 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540649 | 0.86 | SLC2A1 (0.66) | SLC2A1ALKCCNKCCND3CDK9 | |
| SCHEMBL30378896 | 0.86 | SLC2A1 (0.66) | SLC2A1ALKCCNKCCND3CDK9 | |
| SCHEMBL30378928 | 0.85 | SLC2A1 (0.56) | SLC2A1ALKCCNKCCND3CDK9 | |
| SCHEMBL21596319 | 0.85 | SLC2A1 (0.56) | SLC2A1ALKCCNKCCND3CDK9 | |
| SCHEMBL21596307 | 0.83 | JAK3 (0.64) | SLC2A1JAK3FGFR1MAP2K1EGFR | |
| SCHEMBL24773121 | 0.77 | SLC2A1 (0.53) | SLC2A1ALKCDK9PKMYT1JAK3 | |
| SCHEMBL14001919 | 0.77 | ALK (0.77) | ALKCCNKCCND3CDK9CDK6 | |
| SCHEMBL24773089 | 0.77 | SLC2A1 (0.63) | SLC2A1ALKCCNKCCND3CDK9 | |
| SCHEMBL2482380 | 0.76 | SLC2A1 (0.65) | SLC2A1ALKCCNKCCND3CDK9 | |
| SCHEMBL25031904 | 0.75 | SLC2A1 (0.71) | SLC2A1ALKCCNKCCND3CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019242689-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2019-12-26 | — | — | WO | disclosed |