Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.66 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.55 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 4/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CCND3 | P30281 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30378896 | 1.00 | SLC2A1 (0.66) | SLC2A1PKMYT1JAK3ALKSTAT6 | |
| SCHEMBL21600787 | 0.86 | SLC2A1 (0.60) | SLC2A1PKMYT1JAK3ALKBRD4 | |
| SCHEMBL21596307 | 0.84 | JAK3 (0.64) | SLC2A1JAK3EGFR | |
| SCHEMBL21596319 | 0.82 | SLC2A1 (0.56) | SLC2A1PKMYT1JAK3ALKBRD4 | |
| SCHEMBL30378928 | 0.82 | SLC2A1 (0.56) | SLC2A1PKMYT1JAK3ALKBRD4 | |
| SCHEMBL28910563 | 0.78 | SLC2A1 (0.48) | SLC2A1PKMYT1JAK3ALKMAP4K1 | |
| SCHEMBL28525616 | 0.78 | WEE1 (0.57) | SLC2A1PKMYT1JAK3ALKPLK1 | |
| SCHEMBL30379743 | 0.78 | WEE1 (0.53) | SLC2A1PKMYT1JAK3ALKSTAT6 | |
| SCHEMBL28537285 | 0.78 | WEE1 (0.53) | SLC2A1PKMYT1JAK3ALKSTAT6 | |
| SCHEMBL21601021 | 0.76 | MAP3K7 (0.59) | SLC2A1JAK3FLT3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-112313207-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-02-02 | — | — | CN | disclosed |