SCHEMBL2160128

SCHEMBL2160128

CCCC1=Cc2ccccc2C1[Hf]C1C(CCC)=Cc2ccccc21.CCCCC1=Cc2ccccc2C1[Hf]C1C(CCCC)=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814942 0.97 CYP3A4 (0.33) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL29960196 0.97 CYP3A4 (0.33) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL813039 0.94 CYP11B1 (0.30)
SCHEMBL30638593 0.94 CYP11B1 (0.30)
SCHEMBL2160134 0.78 CYP3A4 (0.32) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL815618 0.77 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL29213166 0.77 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Fluoride Ion SCHEMBL1131501 0.76 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL11590486 0.76 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL18242642 0.76 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8633286-B2 Catalyst compositions comprising support materials having an improved particle-size distribution UNIVATION TECHNOLOGIES, LLC (US) 2014-01-21 US disclosed
US-20110184132-A1 Catalyst Compositions Comprising Support Materials Having an Improved Particle-Size Distribution UNIVATION TECHNOLOGIES, LLC (US) 2011-07-28 US disclosed