SCHEMBL814942

SCHEMBL814942

CCCCC1=Cc2ccccc2C1[Hf]C1C(CCCC)=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
HTR5A P47898 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29960196 1.00 CYP3A4 (0.33) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL2160128 0.97 CYP3A4 (0.32) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL30638593 0.90 CYP11B1 (0.30)
SCHEMBL813039 0.90 CYP11B1 (0.30)
SCHEMBL815618 0.79 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL29213166 0.79 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL18242642 0.78 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Fluoride Ion SCHEMBL1131501 0.78 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL11590486 0.78 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL10644406 0.78 TSHR (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901391-B System and method for producing supported catalysts 埃克森美孚化学专利公司 2024-11-26 CN disclosed
US-11618791-B2 Systems and methods for producing a supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-04-04 US disclosed
CN-114901391-A System and method for producing supported catalysts 埃克森美孚化学专利公司 2022-08-12 CN disclosed
WO-2021108049-A1 SYSTEMS AND METHODS FOR PRODUCING A SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-03 WO disclosed
US-20210155723-A1 Systems and Methods for Producing a Supported Catalyst EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-05-27 US disclosed
EP-2872539-B1 INCREASED POLYMER MELT FLOW RATIO VIA FEED OF A SUPPORTED CATALYST SATURATED WITH A SELECTED LIQUID AGENT UNIVATION TECH LLC (US) 2020-12-09 EP disclosed
US-9512254-B2 Increased polymer melt flow ratio via feed of a supported catalyst saturated with a selected liquid agent UNIVATION TECHNOLOGIES, LLC (US) 2016-12-06 US disclosed
EP-1716183-B1 DE-FOAMING SPRAY DRIED CATALYST SLURRIES UNIVATION TECH LLC (US) 2016-04-13 EP disclosed
US-20160032034-A1 HAFNOCENE CATALYZED POLYETHYLENE FILMS HAVING RAPID CLING DEVELOPMENT UNIVATION TECHNOLOGIES, LLC (US) 2016-02-04 US disclosed
EP-2970610-A2 HAFNOCENE CATALYZED POLYETHYLENE FILMS HAVING RAPID CLING DEVELOPMENT Univation Technologies, LLC (US) 2016-01-20 EP disclosed
US-6753390-B2 ADDITION POLYMERIZATION; COMBINING HYDROGEN AND ETHYLENE IN SUPPORTED BIMETALLIC CATALYST SYSTEM COMPRISING METALLOCENE IN FLUIDIZED BED UNIVATION TECHNOLOGIES, LLC 2004-06-22 US disclosed
US-20040092387-A1 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC 2004-05-13 US disclosed
WO-2004022607-A1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
WO-2004022605-A1 GAS PHASE POLYMERIZATION PROCESS UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
US-20040044153-A1 Gas phase polymerization process UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040043893-A1 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040044154-A1 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO disclosed
US-20030171514-A1 Polymerization catalyst activator complexes and their use in a polymerization process DOW GLOBAL TECHNOLOGIES LLC 2003-09-11 US disclosed
WO-2003064435-A1 POLYMERIZATION CATALYST ACTIVATOR COMPLEXES AND THEIR USE IN A POLYMERIZATION PROCESS UNIVATION TECHNOLOGIES, LLC (US) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043893-A1 Process for producing fluorinated catalysts FLI1, AFF1, INF2 CYP3A4 1973/4885CYP2D6 2191/4885CYP2C9 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.