Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HTR1B | P28222 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 7/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591551 | 0.87 | HTR1B (0.65) | KDM4EHTR1BL3MBTL1SCN8AHTR1D | |
| Hydrochloric Acid SCHEMBL2718257 | 0.85 | HTR1B (0.62) | KDM4EHTR1BL3MBTL1SCN8AHTR1D | |
| SCHEMBL7700722 | 0.82 | SCN8A (0.60) | KDM4EHTR1BSCN8AHTR1AALDH1A1 | |
| SCHEMBL21601434 | 0.81 | HTR1B (0.44) | KDM4EHTR1BL3MBTL1SCN8AHTR1D | |
| SCHEMBL21595968 | 0.81 | L3MBTL1 (0.56) | KDM4EGAAMAPTRAB9AL3MBTL1 | |
| SCHEMBL16572858 | 0.80 | KDM4E (0.68) | KDM4EGAAMAPTRAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL21595936 | 0.80 | HTR1B (0.43) | KDM4EHTR1BL3MBTL1SCN8AHTR1D | |
| SCHEMBL21601403 | 0.79 | KDM4E (0.61) | KDM4EGAAMAPTRAB9AL3MBTL1 | |
| SCHEMBL8301647 | 0.79 | KDM4E (0.61) | KDM4EGAAMAPTRAB9AL3MBTL1 | |
| SCHEMBL15346315 | 0.77 | ATM (0.57) | KDM4EGAAMAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244066-A2 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2019-12-26 | — | — | WO | disclosed |