Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 15/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697428 | 0.94 | ALDH1A1 (0.63) | SCN8AHTR1BKDM4EALDH1A1SLC6A4 | |
| SCHEMBL5591551 | 0.94 | HTR1B (0.65) | SCN8AHTR1BKDM4EALDH1A1HTR1A | |
| Hydrochloric Acid SCHEMBL2718257 | 0.92 | HTR1B (0.62) | SCN8AHTR1BKDM4EALDH1A1HTR1A | |
| SCHEMBL21601469 | 0.82 | KDM4E (0.58) | SCN8AHTR1BKDM4EALDH1A1HTR1A | |
| SCHEMBL10693265 | 0.81 | SLC6A4 (0.49) | SCN8AHTR1BKDM4EALDH1A1SLC6A4 | |
| SCHEMBL10987681 | 0.79 | L3MBTL1 (0.67) | SCN8AHTR1BKDM4EALDH1A1SLC6A4 | |
| SCHEMBL19668470 | 0.78 | SCN8A (0.54) | SCN8AKDM4EALDH1A1HTR1AADRA1D | |
| SCHEMBL38662857 | 0.78 | SCN8A (0.58) | SCN8AHTR1BKDM4EALDH1A1HTR1A | |
| SCHEMBL13633202 | 0.78 | HTR1B (0.66) | HTR1BKDM4EALDH1A1SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL10985845 | 0.78 | LMNA (0.68) | SCN8AHTR1BKDM4EALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037871-B1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2002-07-03 | — | — | EP | disclosed |
| EP-1037871-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029655-A1 | NOVEL ANTIARRHYTHMIC COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 1999-06-17 | — | — | WO | disclosed |